SCOREO trial interim safety results: despite efficacy, late stent thrombosis with the QuaDDS-QP2 stent

Late coronary stent thrombosis.

Introduced 20 years ago,1 coronary artery stents have improved the safety and particularly the efficacy of percutaneous coronary interventions (PCIs).2 Abrupt vessel closure, complicating 6% to 8% of balloon angioplasty procedures, was associated with a 5% mortality, 40% rate of myocardial infarction (MI), and 40% rate of emergency coronary artery bypass grafting.3 Stents significantly reduced ...

Very late stent thrombosis due to late stent malapposition.

Very Late Stent Thrombosis Due to Late Stent Malapposition

High-dose 7-hexanoyltaxol-eluting stent with polymer sleeves for coronary revascularization: one-year results from the SCORE randomized trial.

OBJECTIVES The Study to COmpare REstenosis Rate between QueST and QuaDDS-QP2 (SCORE) trial was a multicenter, randomized, open-label trial comparing the safety and performance of 13- and 17-mm QuaDDS stents (n = 126) (Quanam Medical Corp., Santa Clara, California/Boston Scientific Corp., Natick, Massachusetts) versus uncoated control stents (n = 140) in focal, de novo coronary lesions. BACKGR...

Safety, Efficacy and Clinical Outcome of Direct Stent Implantation

Conventional methods of stenting require predilatation, which potentially increase vessel wall injury and cost of the procedure. In this study, the safety and efficacy of direct AVE-S7 (Medtronic-USA) stent placement were evaluated in 100 patients. Quantitative coronary angiography was performed at the baseline and post-stent. Clinical follow-up was done up to 9 months. In 100 patients (76 male...